Provided by: libhmsbeagle-dev_3.1.2+dfsg-13build1_amd64 bug

NAME

       libhmsbeagle/beagle.h - This file documents the API as well as header for the Broad-platform Evolutionary
       Analysis General Likelihood Evaluator.

SYNOPSIS

       #include 'libhmsbeagle/platform.h'

   Classes
       struct BeagleInstanceDetails
           Information about a specific instance.
       struct BeagleResource
           Description of a hardware resource.
       struct BeagleResourceList
           List of hardware resources.
       struct BeagleBenchmarkedResource
           Description of a benchmarked hardware resource.
       struct BeagleBenchmarkedResourceList
           Ordered list of benchmarked hardware resources, from fastest to slowest.
       struct BeagleOperation
           A list of integer indices which specify a partial likelihoods operation.
       struct BeagleOperationByPartition
           A list of integer indices which specify a partial likelihoods operation for a partitioned analysis.

   Enumerations
       enum BeagleReturnCodes { BEAGLE_SUCCESS = 0, BEAGLE_ERROR_GENERAL = -1, BEAGLE_ERROR_OUT_OF_MEMORY = -2,
           BEAGLE_ERROR_UNIDENTIFIED_EXCEPTION = -3, BEAGLE_ERROR_UNINITIALIZED_INSTANCE = -4,
           BEAGLE_ERROR_OUT_OF_RANGE = -5, BEAGLE_ERROR_NO_RESOURCE = -6, BEAGLE_ERROR_NO_IMPLEMENTATION = -7,
           BEAGLE_ERROR_FLOATING_POINT = -8 }
           Error return codes.
       enum BeagleFlags { BEAGLE_FLAG_PRECISION_SINGLE = 1 << 0, BEAGLE_FLAG_PRECISION_DOUBLE = 1 << 1,
           BEAGLE_FLAG_COMPUTATION_SYNCH = 1 << 2, BEAGLE_FLAG_COMPUTATION_ASYNCH = 1 << 3,
           BEAGLE_FLAG_EIGEN_REAL = 1 << 4, BEAGLE_FLAG_EIGEN_COMPLEX = 1 << 5, BEAGLE_FLAG_SCALING_MANUAL = 1
           << 6, BEAGLE_FLAG_SCALING_AUTO = 1 << 7, BEAGLE_FLAG_SCALING_ALWAYS = 1 << 8,
           BEAGLE_FLAG_SCALING_DYNAMIC = 1 << 25, BEAGLE_FLAG_SCALERS_RAW = 1 << 9, BEAGLE_FLAG_SCALERS_LOG = 1
           << 10, BEAGLE_FLAG_INVEVEC_STANDARD = 1 << 20, BEAGLE_FLAG_INVEVEC_TRANSPOSED = 1 << 21,
           BEAGLE_FLAG_VECTOR_SSE = 1 << 11, BEAGLE_FLAG_VECTOR_AVX = 1 << 24, BEAGLE_FLAG_VECTOR_NONE = 1 <<
           12, BEAGLE_FLAG_THREADING_CPP = 1 << 30, BEAGLE_FLAG_THREADING_OPENMP = 1 << 13,
           BEAGLE_FLAG_THREADING_NONE = 1 << 14, BEAGLE_FLAG_PROCESSOR_CPU = 1 << 15, BEAGLE_FLAG_PROCESSOR_GPU
           = 1 << 16, BEAGLE_FLAG_PROCESSOR_FPGA = 1 << 17, BEAGLE_FLAG_PROCESSOR_CELL = 1 << 18,
           BEAGLE_FLAG_PROCESSOR_PHI = 1 << 19, BEAGLE_FLAG_PROCESSOR_OTHER = 1 << 26,
           BEAGLE_FLAG_FRAMEWORK_CUDA = 1 << 22, BEAGLE_FLAG_FRAMEWORK_OPENCL = 1 << 23,
           BEAGLE_FLAG_FRAMEWORK_CPU = 1 << 27, BEAGLE_FLAG_PARALLELOPS_STREAMS = 1 << 28,
           BEAGLE_FLAG_PARALLELOPS_GRID = 1 << 29 }
           Hardware and implementation capability flags.
       enum BeagleBenchmarkFlags { BEAGLE_BENCHFLAG_SCALING_NONE = 1 << 0, BEAGLE_BENCHFLAG_SCALING_ALWAYS = 1
           << 1, BEAGLE_BENCHFLAG_SCALING_DYNAMIC = 1 << 2 }
           Benchmarking mode flags for resource performance evaluation with beagleGetOrderedResourceList.
       enum BeagleOpCodes { BEAGLE_OP_COUNT = 7, BEAGLE_PARTITION_OP_COUNT = 9, BEAGLE_OP_NONE = -1 }
           Operation codes.

   Functions
       BEAGLE_DLLEXPORT const char * beagleGetVersion (void)
           Get version.
       BEAGLE_DLLEXPORT const char * beagleGetCitation (void)
           Get citation.
       BEAGLE_DLLEXPORT BeagleResourceList * beagleGetResourceList (void)
           Get list of hardware resources.
       BEAGLE_DLLEXPORT BeagleBenchmarkedResourceList * beagleGetBenchmarkedResourceList (int tipCount, int
           compactBufferCount, int stateCount, int patternCount, int categoryCount, int *resourceList, int
           resourceCount, long preferenceFlags, long requirementFlags, int eigenModelCount, int partitionCount,
           int calculateDerivatives, long benchmarkFlags)
           Get a benchmarked list of hardware resources for the given analysis parameters.
       BEAGLE_DLLEXPORT int beagleCreateInstance (int tipCount, int partialsBufferCount, int compactBufferCount,
           int stateCount, int patternCount, int eigenBufferCount, int matrixBufferCount, int categoryCount, int
           scaleBufferCount, int *resourceList, int resourceCount, long preferenceFlags, long requirementFlags,
           BeagleInstanceDetails *returnInfo)
           Create a single instance.
       BEAGLE_DLLEXPORT int beagleFinalizeInstance (int instance)
           Finalize this instance.
       BEAGLE_DLLEXPORT int beagleFinalize (void)
           Finalize the library.
       BEAGLE_DLLEXPORT int beagleSetCPUThreadCount (int instance, int threadCount)
           Set number of threads for native CPU implementation.
       BEAGLE_DLLEXPORT int beagleSetTipStates (int instance, int tipIndex, const int *inStates)
           Set the compact state representation for tip node.
       BEAGLE_DLLEXPORT int beagleSetTipPartials (int instance, int tipIndex, const double *inPartials)
           Set an instance partials buffer for tip node.
       BEAGLE_DLLEXPORT int beagleSetPartials (int instance, int bufferIndex, const double *inPartials)
           Set an instance partials buffer.
       BEAGLE_DLLEXPORT int beagleGetPartials (int instance, int bufferIndex, int scaleIndex, double
           *outPartials)
           Get partials from an instance buffer.
       BEAGLE_DLLEXPORT int beagleSetEigenDecomposition (int instance, int eigenIndex, const double
           *inEigenVectors, const double *inInverseEigenVectors, const double *inEigenValues)
           Set an eigen-decomposition buffer.
       BEAGLE_DLLEXPORT int beagleSetStateFrequencies (int instance, int stateFrequenciesIndex, const double
           *inStateFrequencies)
           Set a state frequency buffer.
       BEAGLE_DLLEXPORT int beagleSetCategoryWeights (int instance, int categoryWeightsIndex, const double
           *inCategoryWeights)
           Set a category weights buffer.
       BEAGLE_DLLEXPORT int beagleSetCategoryRates (int instance, const double *inCategoryRates)
           Set the default category rates buffer.
       BEAGLE_DLLEXPORT int beagleSetCategoryRatesWithIndex (int instance, int categoryRatesIndex, const double
           *inCategoryRates)
           Set a category rates buffer.
       BEAGLE_DLLEXPORT int beagleSetPatternWeights (int instance, const double *inPatternWeights)
           Set pattern weights.
       BEAGLE_DLLEXPORT int beagleSetPatternPartitions (int instance, int partitionCount, const int
           *inPatternPartitions)
           Set pattern partition assignments.
       BEAGLE_DLLEXPORT int beagleConvolveTransitionMatrices (int instance, const int *firstIndices, const int
           *secondIndices, const int *resultIndices, int matrixCount)
           Set partitions by pattern weight.
       BEAGLE_DLLEXPORT int beagleUpdateTransitionMatrices (int instance, int eigenIndex, const int
           *probabilityIndices, const int *firstDerivativeIndices, const int *secondDerivativeIndices, const
           double *edgeLengths, int count)
           Calculate a list of transition probability matrices.
       BEAGLE_DLLEXPORT int beagleUpdateTransitionMatricesWithMultipleModels (int instance, const int
           *eigenIndices, const int *categoryRateIndices, const int *probabilityIndices, const int
           *firstDerivativeIndices, const int *secondDerivativeIndices, const double *edgeLengths, int count)
           Calculate a list of transition probability matrices with multiple models.
       BEAGLE_DLLEXPORT int beagleSetTransitionMatrix (int instance, int matrixIndex, const double *inMatrix,
           double paddedValue)
           Set a finite-time transition probability matrix.
       BEAGLE_DLLEXPORT int beagleGetTransitionMatrix (int instance, int matrixIndex, double *outMatrix)
           Get a finite-time transition probability matrix.
       BEAGLE_DLLEXPORT int beagleSetTransitionMatrices (int instance, const int *matrixIndices, const double
           *inMatrices, const double *paddedValues, int count)
           Set multiple transition matrices.
       BEAGLE_DLLEXPORT int beagleUpdatePartials (const int instance, const BeagleOperation *operations, int
           operationCount, int cumulativeScaleIndex)
           Calculate or queue for calculation partials using a list of operations.
       BEAGLE_DLLEXPORT int beagleUpdatePartialsByPartition (const int instance, const
           BeagleOperationByPartition *operations, int operationCount)
           Calculate or queue for calculation partials using a list of partition operations.
       BEAGLE_DLLEXPORT int beagleWaitForPartials (const int instance, const int *destinationPartials, int
           destinationPartialsCount)
           Block until all calculations that write to the specified partials have completed.
       BEAGLE_DLLEXPORT int beagleAccumulateScaleFactors (int instance, const int *scaleIndices, int count, int
           cumulativeScaleIndex)
           Accumulate scale factors.
       BEAGLE_DLLEXPORT int beagleAccumulateScaleFactorsByPartition (int instance, const int *scaleIndices, int
           count, int cumulativeScaleIndex, int partitionIndex)
           Accumulate scale factors by partition.
       BEAGLE_DLLEXPORT int beagleRemoveScaleFactors (int instance, const int *scaleIndices, int count, int
           cumulativeScaleIndex)
           Remove scale factors.
       BEAGLE_DLLEXPORT int beagleRemoveScaleFactorsByPartition (int instance, const int *scaleIndices, int
           count, int cumulativeScaleIndex, int partitionIndex)
           Remove scale factors by partition.
       BEAGLE_DLLEXPORT int beagleResetScaleFactors (int instance, int cumulativeScaleIndex)
           Reset scalefactors.
       BEAGLE_DLLEXPORT int beagleResetScaleFactorsByPartition (int instance, int cumulativeScaleIndex, int
           partitionIndex)
           Reset scalefactors by partition.
       BEAGLE_DLLEXPORT int beagleCopyScaleFactors (int instance, int destScalingIndex, int srcScalingIndex)
           Copy scale factors.
       BEAGLE_DLLEXPORT int beagleGetScaleFactors (int instance, int srcScalingIndex, double *outScaleFactors)
           Get scale factors.
       BEAGLE_DLLEXPORT int beagleCalculateRootLogLikelihoods (int instance, const int *bufferIndices, const int
           *categoryWeightsIndices, const int *stateFrequenciesIndices, const int *cumulativeScaleIndices, int
           count, double *outSumLogLikelihood)
           Calculate site log likelihoods at a root node.
       BEAGLE_DLLEXPORT int beagleCalculateRootLogLikelihoodsByPartition (int instance, const int
           *bufferIndices, const int *categoryWeightsIndices, const int *stateFrequenciesIndices, const int
           *cumulativeScaleIndices, const int *partitionIndices, int partitionCount, int count, double
           *outSumLogLikelihoodByPartition, double *outSumLogLikelihood)
           Calculate site log likelihoods at a root node with per partition buffers.
       BEAGLE_DLLEXPORT int beagleCalculateEdgeLogLikelihoods (int instance, const int *parentBufferIndices,
           const int *childBufferIndices, const int *probabilityIndices, const int *firstDerivativeIndices,
           const int *secondDerivativeIndices, const int *categoryWeightsIndices, const int
           *stateFrequenciesIndices, const int *cumulativeScaleIndices, int count, double *outSumLogLikelihood,
           double *outSumFirstDerivative, double *outSumSecondDerivative)
           Calculate site log likelihoods and derivatives along an edge.
       BEAGLE_DLLEXPORT int beagleCalculateEdgeLogLikelihoodsByPartition (int instance, const int
           *parentBufferIndices, const int *childBufferIndices, const int *probabilityIndices, const int
           *firstDerivativeIndices, const int *secondDerivativeIndices, const int *categoryWeightsIndices, const
           int *stateFrequenciesIndices, const int *cumulativeScaleIndices, const int *partitionIndices, int
           partitionCount, int count, double *outSumLogLikelihoodByPartition, double *outSumLogLikelihood,
           double *outSumFirstDerivativeByPartition, double *outSumFirstDerivative, double
           *outSumSecondDerivativeByPartition, double *outSumSecondDerivative)
           Calculate multiple site log likelihoods and derivatives along an edge with per partition buffers.
       BEAGLE_DLLEXPORT int beagleGetLogLikelihood (int instance, double *outSumLogLikelihood)
           Returns log likelihood sum and subsequent to an asynchronous integration call.
       BEAGLE_DLLEXPORT int beagleGetDerivatives (int instance, double *outSumFirstDerivative, double
           *outSumSecondDerivative)
           Returns derivative sums subsequent to an asynchronous integration call.
       BEAGLE_DLLEXPORT int beagleGetSiteLogLikelihoods (int instance, double *outLogLikelihoods)
           Get site log likelihoods for last beagleCalculateRootLogLikelihoods or
           beagleCalculateEdgeLogLikelihoods call.
       BEAGLE_DLLEXPORT int beagleGetSiteDerivatives (int instance, double *outFirstDerivatives, double
           *outSecondDerivatives)
           Get site derivatives for last beagleCalculateEdgeLogLikelihoods call.

Detailed Description

       This file documents the API as well as header for the Broad-platform Evolutionary Analysis General
       Likelihood Evaluator.

       Copyright 2009-2013 Phylogenetic Likelihood Working Group

       This file is part of BEAGLE.

       BEAGLE is free software: you can redistribute it and/or modify it under the terms of the GNU Lesser
       General Public License as published by the Free Software Foundation, either version 3 of the License, or
       (at your option) any later version.

       BEAGLE is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the
       implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General
       Public License for more details.

       You should have received a copy of the GNU Lesser General Public License along with BEAGLE. If not, see
       http://www.gnu.org/licenses/.

       KEY CONCEPTS

       The key to BEAGLE performance lies in delivering fine-scale parallelization while minimizing data
       transfer and memory copy overhead. To accomplish this, the library lacks the concept of data structure
       for a tree, in spite of the intended use for phylogenetic analysis. Instead, BEAGLE acts directly on
       flexibly indexed data storage (called buffers) for observed character states and partial likelihoods. The
       client program can set the input buffers to reflect the data and can calculate the likelihood of a
       particular phylogeny by invoking likelihood calculations on the appropriate input and output buffers in
       the correct order. Because of this design simplicity, the library can support many different tree
       inference algorithms and likelihood calculation on a variety of models. Arbitrary numbers of states can
       be used, as can nonreversible substitution matrices via complex eigen decompositions, and mixture models
       with multiple rate categories and/or multiple eigen decompositions. Finally, BEAGLE application
       programming interface (API) calls can be asynchronous, allowing the calling program to implement other
       coarse-scale parallelization schemes such as evaluating independent genes or running concurrent Markov
       chains.

       USAGE

       To use the library, a client program first creates an instance of BEAGLE by calling beagleCreateInstance;
       multiple instances per client are possible and encouraged. All additional functions are called with a
       reference to this instance. The client program can optionally request that an instance run on certain
       hardware (e.g., a GPU) or have particular features (e.g., double-precision math). Next, the client
       program must specify the data dimensions and specify key aspects of the phylogenetic model. Character
       state data are then loaded and can be in the form of discrete observed states or partial likelihoods for
       ambiguous characters. The observed data are usually unchanging and loaded only once at the start to
       minimize memory copy overhead. The character data can be compressed into unique “site patterns” and
       associated weights for each. The parameters of the substitution process can then be specified, including
       the equilibrium state frequencies, the rates for one or more substitution rate categories and their
       weights, and finally, the eigen decomposition for the substitution process.

       In order to calculate the likelihood of a particular tree, the client program then specifies a series of
       integration operations that correspond to steps in Felsenstein’s algorithm. Finite-time transition
       probabilities for each edge are loaded directly if considering a nondiagonalizable model or calculated in
       parallel from the eigen decomposition and edge lengths specified. This is performed within BEAGLE’s
       memory space to minimize data transfers. A single function call will then request one or more integration
       operations to calculate partial likelihoods over some or all nodes. The operations are performed in the
       order they are provided, typically dictated by a postorder traversal of the tree topology. The client
       needs only specify nodes for which the partial likelihoods need updating, but it is up to the calling
       software to keep track of these dependencies. The final step in evaluating the phylogenetic model is done
       using an API call that yields a single log likelihood for the model given the data.

       Aspects of the BEAGLE API design support both maximum likelihood (ML) and Bayesian phylogenetic tree
       inference. For ML inference, API calls can calculate first and second derivatives of the likelihood with
       respect to the lengths of edges (branches). In both cases, BEAGLE provides the ability to cache and reuse
       previously computed partial likelihood results, which can yield a tremendous speedup over recomputing the
       entire likelihood every time a new phylogenetic model is evaluated.

       Author
           Likelihood API Working Group

           Daniel Ayres

           Peter Beerli

           Michael Cummings

           Aaron Darling

           Mark Holder

           John Huelsenbeck

           Paul Lewis

           Michael Ott

           Andrew Rambaut

           Fredrik Ronquist

           Marc Suchard

           David Swofford

           Derrick Zwickl

Enumeration Type Documentation

   enum BeagleBenchmarkFlags
       Benchmarking mode flags for resource performance evaluation with beagleGetOrderedResourceList.

       This enumerates all possible benchmarking mode flags. Each mode is a bit in a 'long'

       Enumerator

       BEAGLE_BENCHFLAG_SCALING_NONE
              No scaling

       BEAGLE_BENCHFLAG_SCALING_ALWAYS
              Scale at every iteration

       BEAGLE_BENCHFLAG_SCALING_DYNAMIC
              Scale  every fixed number of iterations or when a numerical error occurs, and re-use scale factors
              for subsequent iterations

   enum BeagleFlags
       Hardware and implementation capability flags.

       This enumerates all possible hardware and implementation capability flags. Each capability is a bit in  a
       'long'

       Enumerator

       BEAGLE_FLAG_PRECISION_SINGLE
              Single precision computation

       BEAGLE_FLAG_PRECISION_DOUBLE
              Double precision computation

       BEAGLE_FLAG_COMPUTATION_SYNCH
              Synchronous computation (blocking)

       BEAGLE_FLAG_COMPUTATION_ASYNCH
              Asynchronous computation (non-blocking)

       BEAGLE_FLAG_EIGEN_REAL
              Real eigenvalue computation

       BEAGLE_FLAG_EIGEN_COMPLEX
              Complex eigenvalue computation

       BEAGLE_FLAG_SCALING_MANUAL
              Manual scaling

       BEAGLE_FLAG_SCALING_AUTO
              Auto-scaling on (deprecated, may not work correctly)

       BEAGLE_FLAG_SCALING_ALWAYS
              Scale at every updatePartials (deprecated, may not work correctly)

       BEAGLE_FLAG_SCALING_DYNAMIC
              Manual scaling with dynamic checking (deprecated, may not work correctly)

       BEAGLE_FLAG_SCALERS_RAW
              Save raw scalers

       BEAGLE_FLAG_SCALERS_LOG
              Save log scalers

       BEAGLE_FLAG_INVEVEC_STANDARD
              Inverse eigen vectors passed to BEAGLE have not been transposed

       BEAGLE_FLAG_INVEVEC_TRANSPOSED
              Inverse eigen vectors passed to BEAGLE have been transposed

       BEAGLE_FLAG_VECTOR_SSE
              SSE computation

       BEAGLE_FLAG_VECTOR_AVX
              AVX computation

       BEAGLE_FLAG_VECTOR_NONE
              No vector computation

       BEAGLE_FLAG_THREADING_CPP
              C++11 threading

       BEAGLE_FLAG_THREADING_OPENMP
              OpenMP threading

       BEAGLE_FLAG_THREADING_NONE
              No threading (default)

       BEAGLE_FLAG_PROCESSOR_CPU
              Use CPU as main processor

       BEAGLE_FLAG_PROCESSOR_GPU
              Use GPU as main processor

       BEAGLE_FLAG_PROCESSOR_FPGA
              Use FPGA as main processor

       BEAGLE_FLAG_PROCESSOR_CELL
              Use Cell as main processor

       BEAGLE_FLAG_PROCESSOR_PHI
              Use Intel Phi as main processor

       BEAGLE_FLAG_PROCESSOR_OTHER
              Use other type of processor

       BEAGLE_FLAG_FRAMEWORK_CUDA
              Use CUDA implementation with GPU resources

       BEAGLE_FLAG_FRAMEWORK_OPENCL
              Use OpenCL implementation with GPU resources

       BEAGLE_FLAG_FRAMEWORK_CPU
              Use CPU implementation

       BEAGLE_FLAG_PARALLELOPS_STREAMS
              Operations in updatePartials may be assigned to separate device streams

       BEAGLE_FLAG_PARALLELOPS_GRID
              Operations  in  updatePartials  may be folded into single kernel launch (necessary for partitions;
              typically performs better for problems with fewer pattern sites)

   enum BeagleOpCodes
       Operation codes.

       This enumerates all possible BEAGLE operation codes.

       Enumerator

       BEAGLE_OP_COUNT
              Total number of integers per beagleUpdatePartials operation

       BEAGLE_PARTITION_OP_COUNT
              Total number of integers per beagleUpdatePartialsByPartition operation

       BEAGLE_OP_NONE
              Specify no use for indexed buffer

   enum BeagleReturnCodes
       Error return codes.

       This enumerates all possible BEAGLE return codes. Error codes are always negative.

       Enumerator

       BEAGLE_SUCCESS
              Success

       BEAGLE_ERROR_GENERAL
              Unspecified error

       BEAGLE_ERROR_OUT_OF_MEMORY
              Not enough memory could be allocated

       BEAGLE_ERROR_UNIDENTIFIED_EXCEPTION
              Unspecified exception

       BEAGLE_ERROR_UNINITIALIZED_INSTANCE
              The instance index is out of range, or the instance has not been created

       BEAGLE_ERROR_OUT_OF_RANGE
              One of the indices specified exceeded the range of the array

       BEAGLE_ERROR_NO_RESOURCE
              No resource matches requirements

       BEAGLE_ERROR_NO_IMPLEMENTATION
              No implementation matches requirements

       BEAGLE_ERROR_FLOATING_POINT
              Floating-point error (e.g., NaN)

Function Documentation

   BEAGLE_DLLEXPORT int beagleAccumulateScaleFactors (int instance, const int *  scaleIndices,  int  count,  int
       cumulativeScaleIndex)
       Accumulate  scale  factors.  This  function  adds  (log)  scale  factors from a list of scaleBuffers to a
       cumulative scale buffer. It is used to calculate the marginal scaling at a specific node for each site.

       Parameters
           instance Instance number (input)
           scaleIndices List of scaleBuffers to add (input)
           count Number of scaleBuffers in list (input)
           cumulativeScaleIndex Index number of scaleBuffer to accumulate factors into (input)

   BEAGLE_DLLEXPORT int beagleAccumulateScaleFactorsByPartition (int instance, const  int  *  scaleIndices,  int
       count, int cumulativeScaleIndex, int partitionIndex)
       Accumulate scale factors by partition. This function adds (log) scale factors from a list of scaleBuffers
       to  a  cumulative  scale buffer. It is used to calculate the marginal scaling at a specific node for each
       site.

       Parameters
           instance Instance number (input)
           scaleIndices List of scaleBuffers to add (input)
           count Number of scaleBuffers in list (input)
           cumulativeScaleIndex Index number of scaleBuffer to accumulate factors into (input)
           partitionIndex Index of partition to accumulate into (input)

   BEAGLE_DLLEXPORT int beagleCalculateEdgeLogLikelihoods (int instance, const int * parentBufferIndices,  const
       int * childBufferIndices, const int * probabilityIndices, const int * firstDerivativeIndices, const int *
       secondDerivativeIndices,  const  int * categoryWeightsIndices, const int * stateFrequenciesIndices, const
       int * cumulativeScaleIndices, int count, double * outSumLogLikelihood,  double  *  outSumFirstDerivative,
       double * outSumSecondDerivative)
       Calculate site log likelihoods and derivatives along an edge. This function integrates a list of partials
       at  a parent and child node with respect to a set of partials-weights and state frequencies to return the
       log likelihood and first and second derivative sums

       Parameters
           instance Instance number (input)
           parentBufferIndices List of indices of parent partialsBuffers (input)
           childBufferIndices List of indices of child partialsBuffers (input)
           probabilityIndices List indices of transition probability matrices for this edge (input)
           firstDerivativeIndices List indices of first derivative matrices (input)
           secondDerivativeIndices List indices of second derivative matrices (input)
           categoryWeightsIndices List of weights to apply to each partialsBuffer (input)
           stateFrequenciesIndices List of state frequencies for each partialsBuffer (input).  There  should  be
           one set for each of parentBufferIndices
           cumulativeScaleIndices  List  of  scaleBuffers  containing  accumulated  factors  to  apply  to  each
           partialsBuffer (input). There should be one index for each of parentBufferIndices
           count Number of partialsBuffers (input)
           outSumLogLikelihood Pointer to destination for resulting log likelihood (output)
           outSumFirstDerivative Pointer to destination for resulting first derivative (output)
           outSumSecondDerivative Pointer to destination for resulting second derivative (output)

       Returns
           error code

   BEAGLE_DLLEXPORT   int   beagleCalculateEdgeLogLikelihoodsByPartition   (int   instance,    const    int    *
       parentBufferIndices,  const  int  *  childBufferIndices,  const  int  *  probabilityIndices,  const int *
       firstDerivativeIndices, const int * secondDerivativeIndices, const int  *  categoryWeightsIndices,  const
       int  *  stateFrequenciesIndices,  const  int  * cumulativeScaleIndices, const int * partitionIndices, int
       partitionCount, int count, double * outSumLogLikelihoodByPartition, double * outSumLogLikelihood,  double
       *      outSumFirstDerivativeByPartition,      double      *      outSumFirstDerivative,      double     *
       outSumSecondDerivativeByPartition, double * outSumSecondDerivative)
       Calculate multiple site log likelihoods and derivatives along an edge with per  partition  buffers.  This
       function  integrates  lists  of  partials  at  a parent and child node with respect to a set of partials-
       weights and state frequencies to return the log likelihood and first and second derivative sums

       Parameters
           instance Instance number (input)
           parentBufferIndices List of indices of parent partialsBuffers (input)
           childBufferIndices List of indices of child partialsBuffers (input)
           probabilityIndices List indices of transition probability matrices for this edge (input)
           firstDerivativeIndices List indices of first derivative matrices (input)
           secondDerivativeIndices List indices of second derivative matrices (input)
           categoryWeightsIndices List of weights to apply to each partialsBuffer (input)
           stateFrequenciesIndices List of state frequencies for each partialsBuffer (input).  There  should  be
           one set for each of parentBufferIndices
           cumulativeScaleIndices  List  of  scaleBuffers  containing  accumulated  factors  to  apply  to  each
           partialsBuffer (input). There should be one index for each of parentBufferIndices
           partitionIndices List of partition indices indicating which sites in each  partialsBuffer  should  be
           used (input). There should be one index for each of parentBufferIndices
           partitionCount Number of distinct partitionIndices (input)
           count Number of sets of partitions to integrate across (input)
           outSumLogLikelihoodByPartition  Pointer  to  destination  for  resulting  log  likelihoods  for  each
           partition (output)
           outSumLogLikelihood Pointer to destination for resulting log likelihood (output)
           outSumFirstDerivativeByPartition Pointer to destination  for  resulting  first  derivative  for  each
           partition (output)
           outSumFirstDerivative Pointer to destination for resulting first derivative (output)
           outSumSecondDerivativeByPartition  Pointer  to  destination  for resulting second derivative for each
           partition (output)
           outSumSecondDerivative Pointer to destination for resulting second derivative (output)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleCalculateRootLogLikelihoods (int instance, const int * bufferIndices, const int  *
       categoryWeightsIndices,  const  int  *  stateFrequenciesIndices,  const int * cumulativeScaleIndices, int
       count, double * outSumLogLikelihood)
       Calculate site log likelihoods at a root node. This function integrates a list of partials at a node with
       respect to a set of partials-weights and state frequencies to return the log likelihood sum

       Parameters
           instance Instance number (input)
           bufferIndices List of partialsBuffer indices to integrate (input)
           categoryWeightsIndices List of weights to apply to each partialsBuffer (input). There should  be  one
           categoryCount sized set for each of parentBufferIndices
           stateFrequenciesIndices  List  of  state frequencies for each partialsBuffer (input). There should be
           one set for each of parentBufferIndices
           cumulativeScaleIndices  List  of  scaleBuffers  containing  accumulated  factors  to  apply  to  each
           partialsBuffer (input). There should be one index for each of parentBufferIndices
           count Number of partialsBuffer to integrate (input)
           outSumLogLikelihood Pointer to destination for resulting log likelihood (output)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleCalculateRootLogLikelihoodsByPartition (int instance, const int * bufferIndices,
       const   int   *   categoryWeightsIndices,   const   int   *   stateFrequenciesIndices,   const   int    *
       cumulativeScaleIndices,   const   int  *  partitionIndices,  int  partitionCount,  int  count,  double  *
       outSumLogLikelihoodByPartition, double * outSumLogLikelihood)
       Calculate site log likelihoods at a root node with per partition buffers. This function integrates  lists
       of  partials  at a node with respect to a set of partials-weights and state frequencies to return the log
       likelihood sums

       Parameters
           instance Instance number (input)
           bufferIndices List of partialsBuffer indices to integrate (input)
           categoryWeightsIndices List of weights to apply to each partialsBuffer (input). There should  be  one
           categoryCount sized set for each of bufferIndices
           stateFrequenciesIndices  List  of  state frequencies for each partialsBuffer (input). There should be
           one set for each of bufferIndices
           cumulativeScaleIndices  List  of  scaleBuffers  containing  accumulated  factors  to  apply  to  each
           partialsBuffer (input). There should be one index for each of bufferIndices
           partitionIndices  List  of  partition indices indicating which sites in each partialsBuffer should be
           used (input). There should be one index for each of bufferIndices
           partitionCount Number of distinct partitionIndices (input)
           count Number of sets of partitions to integrate across (input)
           outSumLogLikelihoodByPartition  Pointer  to  destination  for  resulting  log  likelihoods  for  each
           partition (output)
           outSumLogLikelihood Pointer to destination for resulting log likelihood (output)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleConvolveTransitionMatrices  (int instance, const int * firstIndices, const int *
       secondIndices, const int * resultIndices, int matrixCount)
       Set partitions by pattern weight. This function defines partitions by setting their vectors  of  pattern-
       weights for an instance. It should be called after beagleSetTipPartials or beagleSetTipStates.

       Parameters
           instance Instance number (input)
           inPartitionPatternWeights partitionCount arrays, each containing patternCount pattern weights (input)
           partitionCount Number of partitions (input)

       Returns
           error code

       Convolve lists of transition probability matrices

       This function convolves two lists of transition probability matrices.

       Parameters
           instance Instance number (input)
           firstIndices List of indices of the first transition probability matrices to convolve (input)
           secondIndices List of indices of the second transition probability matrices to convolve (input)
           resultIndices List of indices of resulting transition probability matrices (input)
           matrixCount Length of lists

   BEAGLE_DLLEXPORT int beagleCopyScaleFactors (int instance, int destScalingIndex, int srcScalingIndex)
       Copy scale factors. This function copies scale factors from one buffer to another.

       Parameters
           instance Instance number (input)
           destScalingIndex Destination scaleBuffer (input)
           srcScalingIndex Source scaleBuffer (input)

   BEAGLE_DLLEXPORT int beagleCreateInstance (int tipCount, int partialsBufferCount, int compactBufferCount, int
       stateCount,  int  patternCount,  int  eigenBufferCount,  int  matrixBufferCount,  int  categoryCount, int
       scaleBufferCount, int * resourceList, int resourceCount,  long  preferenceFlags,  long  requirementFlags,
       BeagleInstanceDetails * returnInfo)
       Create a single instance. This function creates a single instance of the BEAGLE library and can be called
       multiple times to create multiple data partition instances each returning a unique identifier.

       Parameters
           tipCount Number of tip data elements (input)
           partialsBufferCount Number of partials buffers to create (input)
           compactBufferCount Number of compact state representation buffers to create (input)
           stateCount Number of states in the continuous-time Markov chain (input)
           patternCount Number of site patterns to be handled by the instance (input)
           eigenBufferCount  Number  of  rate  matrix  eigen-decomposition, category weight, category rates, and
           state frequency buffers to allocate (input)
           matrixBufferCount Number of transition probability matrix buffers (input)
           categoryCount Number of rate categories (input)
           scaleBufferCount Number of scale buffers to create, ignored for auto scale or always scale (input)
           resourceList List of potential resources on which this instance is allowed (input,  NULL  implies  no
           restriction)
           resourceCount Length of resourceList list (input)
           preferenceFlags  Bit-flags  indicating  preferred  implementation  characteristics,  see  BeagleFlags
           (input)
           requirementFlags  Bit-flags  indicating  required  implementation  characteristics,  see  BeagleFlags
           (input)
           returnInfo Pointer to return implementation and resource details

       Returns
           the unique instance identifier (<0 if failed, see BeagleReturnCodes)

   BEAGLE_DLLEXPORT int beagleFinalize (void)
       Finalize  the  library.  This  function  finalizes  the  library  and releases all allocated memory. This
       function is automatically called under GNU C via attribute ((destructor)).

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleFinalizeInstance (int instance)
       Finalize this instance. This function finalizes the instance by releasing allocated memory

       Parameters
           instance Instance number

       Returns
           error code

   BEAGLE_DLLEXPORT  BeagleBenchmarkedResourceList  *  beagleGetBenchmarkedResourceList   (int   tipCount,   int
       compactBufferCount,  int  stateCount,  int  patternCount,  int  categoryCount,  int  *  resourceList, int
       resourceCount, long preferenceFlags, long requirementFlags, int eigenModelCount, int partitionCount,  int
       calculateDerivatives, long benchmarkFlags)
       Get  a  benchmarked list of hardware resources for the given analysis parameters. This function returns a
       pointer to a BeagleBenchmarkedResourceList  struct,  which  includes  a  BeagleBenchmarkedResource  array
       describing  the  available  hardware  resources  with benchmark times and CPU performance ratios for each
       resource. Resources are benchmarked with the given analysis parameters and  the  array  is  ordered  from
       fastest to slowest. If there is an error the function returns NULL.

       Parameters
           tipCount Number of tip data elements (input)
           compactBufferCount Number of compact state representation tips (input)
           stateCount Number of states in the continuous-time Markov chain (input)
           patternCount Number of site patterns (input)
           categoryCount Number of rate categories (input)
           resourceList List of resources to be benchmarked, NULL implies no restriction (input)
           resourceCount Length of resourceList list (input)
           preferenceFlags  Bit-flags  indicating  preferred  implementation  characteristics,  see  BeagleFlags
           (input)
           requirementFlags  Bit-flags  indicating  required  implementation  characteristics,  see  BeagleFlags
           (input)
           eigenModelCount Number of full-alignment rate matrix eigen-decomposition models (input)
           partitionCount Number of partitions (input)
           calculateDerivatives Indicates if calculation of derivatives are required (input)
           benchmarkFlags Bit-flags indicating benchmarking preferences (input)

       Returns
           An  ordered  (fastest  to  slowest)  list  of  hardware  resources  available  to  the  library  as a
           BeagleBenchmarkedResourceList for the specified analysis parameters

   BEAGLE_DLLEXPORT const char * beagleGetCitation (void)
       Get citation. This function returns a pointer to a string describing the version of the library  and  how
       to cite it.

       Returns
           A string describing the version of the library and how to cite it

   BEAGLE_DLLEXPORT   int   beagleGetDerivatives   (int  instance,  double  *  outSumFirstDerivative,  double  *
       outSumSecondDerivative)
       Returns derivative sums subsequent to an asynchronous integration call. This  function  is  optional  and
       only   has   to   be   called  by  clients  that  use  the  non-blocking  asynchronous  computation  mode
       (BEAGLE_FLAG_COMPUTATION_ASYNCH).

       If used, this function must be called after a beagleCalculateEdgeLogLikelihoods call.  The  library  will
       block until the derivatiives have been calculated.

       Parameters
           instance Instance number (input)
           outSumFirstDerivative Pointer to destination for resulting first derivative (output)
           outSumSecondDerivative Pointer to destination for resulting second derivative (output)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleGetLogLikelihood (int instance, double * outSumLogLikelihood)
       Returns  log likelihood sum and subsequent to an asynchronous integration call. This function is optional
       and only  has  to  be  called  by  clients  that  use  the  non-blocking  asynchronous  computation  mode
       (BEAGLE_FLAG_COMPUTATION_ASYNCH).

       If    used,    this    function   must   be   called   after   a   beagleCalculateRootLogLikelihoods   or
       beagleCalculateEdgeLogLikelihoods call. The library will block until the likelihood has been calculated.

       Parameters
           instance Instance number (input)
           outSumLogLikelihood Pointer to destination for resulting log likelihood (output)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleGetPartials (int instance, int bufferIndex, int scaleIndex, double * outPartials)
       Get partials from an instance buffer. This function copies an instance buffer into the array outPartials.
       The outPartials array should be stateCount * patternCount * categoryCount in length.

       Parameters
           instance Instance number from which to get partialsBuffer (input)
           bufferIndex Index of source partialsBuffer (input)
           scaleIndex Index of scaleBuffer to apply to partialsBuffer (input)
           outPartials Pointer to which to receive partialsBuffer (output)

       Returns
           error code

   BEAGLE_DLLEXPORT BeagleResourceList * beagleGetResourceList (void)
       Get list of hardware resources. This function returns a pointer to  a  BeagleResourceList  struct,  which
       includes a BeagleResource array describing the available hardware resources.

       Returns
           A list of hardware resources available to the library as a BeagleResourceList

   BEAGLE_DLLEXPORT int beagleGetScaleFactors (int instance, int srcScalingIndex, double * outScaleFactors)
       Get scale factors. This function retrieves a buffer of scale factors.

       Parameters
           instance Instance number (input)
           srcScalingIndex Source scaleBuffer (input)
           outScaleFactors Pointer to which to receive scaleFactors (output)

   BEAGLE_DLLEXPORT   int  beagleGetSiteDerivatives  (int  instance,  double  *  outFirstDerivatives,  double  *
       outSecondDerivatives)
       Get  site  derivatives  for  last  beagleCalculateEdgeLogLikelihoods  call.  This  function  returns  the
       derivatives for each site

       Parameters
           instance Instance number (input)
           outFirstDerivatives Pointer to destination for resulting first derivatives (output)
           outSecondDerivatives Pointer to destination for resulting second derivatives (output)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleGetSiteLogLikelihoods (int instance, double * outLogLikelihoods)
       Get  site log likelihoods for last beagleCalculateRootLogLikelihoods or beagleCalculateEdgeLogLikelihoods
       call. This function returns the log likelihoods for each site

       Parameters
           instance Instance number (input)
           outLogLikelihoods Pointer to destination for resulting log likelihoods (output)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleGetTransitionMatrix (int instance, int matrixIndex, double * outMatrix)
       Get a finite-time transition probability matrix. This function copies  a  finite-time  transition  matrix
       buffer  into  the  array  outMatrix.  The  outMatrix  array  should  be of size stateCount * stateCount *
       categoryCount and will be filled with one matrix for each rate category.

       Parameters
           instance Instance number (input)
           matrixIndex Index of matrix buffer (input)
           outMatrix Pointer to destination transition probability matrix (output)

       Returns
           error code

   BEAGLE_DLLEXPORT const char * beagleGetVersion (void)
       Get version. This function returns a pointer to a string with the library version number.

       Returns
           A string with the version number

   BEAGLE_DLLEXPORT int beagleRemoveScaleFactors (int  instance,  const  int  *  scaleIndices,  int  count,  int
       cumulativeScaleIndex)
       Remove scale factors. This function removes (log) scale factors from a cumulative scale buffer. The scale
       factors to be removed are indicated in a list of scaleBuffers.

       Parameters
           instance Instance number (input)
           scaleIndices List of scaleBuffers to remove (input)
           count Number of scaleBuffers in list (input)
           cumulativeScaleIndex Index number of scaleBuffer containing accumulated factors (input)

   BEAGLE_DLLEXPORT  int beagleRemoveScaleFactorsByPartition (int instance, const int * scaleIndices, int count,
       int cumulativeScaleIndex, int partitionIndex)
       Remove scale factors by partition. This function removes (log) scale  factors  from  a  cumulative  scale
       buffer. The scale factors to be removed are indicated in a list of scaleBuffers.

       Parameters
           instance Instance number (input)
           scaleIndices List of scaleBuffers to remove (input)
           count Number of scaleBuffers in list (input)
           cumulativeScaleIndex Index number of scaleBuffer containing accumulated factors (input)
           partitionIndex Index of partition to remove from (input)

   BEAGLE_DLLEXPORT int beagleResetScaleFactors (int instance, int cumulativeScaleIndex)
       Reset scalefactors. This function resets a cumulative scale buffer.

       Parameters
           instance Instance number (input)
           cumulativeScaleIndex Index number of cumulative scaleBuffer (input)

   BEAGLE_DLLEXPORT   int   beagleResetScaleFactorsByPartition  (int  instance,  int  cumulativeScaleIndex,  int
       partitionIndex)
       Reset scalefactors by partition. This function resets a cumulative scale buffer.

       Parameters
           instance Instance number (input)
           cumulativeScaleIndex Index number of cumulative scaleBuffer (input)
           partitionIndex Index of partition to reset (input)

   BEAGLE_DLLEXPORT int beagleSetCategoryRates (int instance, const double * inCategoryRates)
       Set the default category rates buffer. This function sets the default vector of  category  rates  for  an
       instance.

       Parameters
           instance Instance number (input)
           inCategoryRates Array containing categoryCount rate scalers (input)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleSetCategoryRatesWithIndex  (int instance, int categoryRatesIndex, const double *
       inCategoryRates)
       Set a category rates buffer. This function sets the vector of category rates for a  given  buffer  in  an
       instance.

       Parameters
           instance Instance number (input)
           categoryRatesIndex Index of category rates buffer (input)
           inCategoryRates Array containing categoryCount rate scalers (input)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleSetCategoryWeights  (int  instance,  int  categoryWeightsIndex,  const  double *
       inCategoryWeights)
       Set a category weights buffer. This function copies a category weights array into an instance buffer.

       Parameters
           instance Instance number (input)
           categoryWeightsIndex Index of category weights buffer (input)
           inCategoryWeights Category weights array (categoryCount) (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetCPUThreadCount (int instance, int threadCount)
       Set number of threads for native CPU implementation. This function sets the max number of worker  threads
       to  be  used  with  a  native CPU implementation. It should only be called after beagleCreateInstance and
       requires the BEAGLE_FLAG_THREADING_CPP flag to be set. It has no effect on GPU-based implementations.  It
       has  no  effect  with the default BEAGLE_FLAG_THREADING_NONE setting. If BEAGLE_FLAG_THREADING_CPP is set
       and this function is not called BEAGLE will use a heuristic to set an appropriate number of threads.

       Parameters
           instance Instance number (input)
           threadCount Number of threads (input)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleSetEigenDecomposition  (int   instance,   int   eigenIndex,   const   double   *
       inEigenVectors, const double * inInverseEigenVectors, const double * inEigenValues)
       Set an eigen-decomposition buffer. This function copies an eigen-decomposition into an instance buffer.

       Parameters
           instance Instance number (input)
           eigenIndex Index of eigen-decomposition buffer (input)
           inEigenVectors Flattened matrix (stateCount x stateCount) of eigen-vectors (input)
           inInverseEigenVectors Flattened matrix (stateCount x stateCount) of inverse-eigen- vectors (input)
           inEigenValues Vector of eigenvalues

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetPartials (int instance, int bufferIndex, const double * inPartials)
       Set  an  instance partials buffer. This function copies an array of partials into an instance buffer. The
       inPartials array should be stateCount * patternCount * categoryCount in length.

       Parameters
           instance Instance number in which to set a partialsBuffer (input)
           bufferIndex Index of destination partialsBuffer (input)
           inPartials Pointer to partials values to set (input)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleSetPatternPartitions  (int   instance,   int   partitionCount,   const   int   *
       inPatternPartitions)
       Set  pattern  partition  assignments.  This  function sets the vector of pattern partition indices for an
       instance. It should only be called after beagleSetTipPartials and beagleSetPatternWeights.

       Parameters
           instance Instance number (input)
           partitionCount Number of partitions (input)
           inPatternPartitions Array containing partitionCount partition indices (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetPatternWeights (int instance, const double * inPatternWeights)
       Set pattern weights. This function sets the vector of pattern weights for an instance.

       Parameters
           instance Instance number (input)
           inPatternWeights Array containing patternCount weights (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetStateFrequencies (int  instance,  int  stateFrequenciesIndex,  const  double  *
       inStateFrequencies)
       Set a state frequency buffer. This function copies a state frequency array into an instance buffer.

       Parameters
           instance Instance number (input)
           stateFrequenciesIndex Index of state frequencies buffer (input)
           inStateFrequencies State frequencies array (stateCount) (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetTipPartials (int instance, int tipIndex, const double * inPartials)
       Set  an instance partials buffer for tip node. This function copies an array of partials into an instance
       buffer. The inPartials array should be stateCount * patternCount in length. For  most  applications  this
       will  be  used  to  set the partial likelihoods for the observed states. Internally, the partials will be
       copied categoryCount times.

       Parameters
           instance Instance number in which to set a partialsBuffer (input)
           tipIndex Index of destination partialsBuffer (input)
           inPartials Pointer to partials values to set (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetTipStates (int instance, int tipIndex, const int * inStates)
       Set the compact state representation for tip node. This function copies a  compact  state  representation
       into an instance buffer. Compact state representation is an array of states: 0 to stateCount - 1 (missing
       =  stateCount).  The inStates array should be patternCount in length (replication across categoryCount is
       not required).

       Parameters
           instance Instance number (input)
           tipIndex Index of destination compactBuffer (input)
           inStates Pointer to compact states (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleSetTransitionMatrices (int instance, const int *  matrixIndices,  const  double  *
       inMatrices, const double * paddedValues, int count)
       Set  multiple transition matrices. This function copies multiple transition matrices into matrix buffers.
       This function is used when the application wishes to explicitly set the transition matrices  rather  than
       using  the beagleSetEigenDecomposition and beagleUpdateTransitionMatrices functions. The inMatrices array
       should be of size stateCount * stateCount * categoryCount * count.

       Parameters
           instance Instance number (input)
           matrixIndices Indices of matrix buffers (input)
           inMatrices Pointer to source transition matrices (input)
           paddedValues Values to be used for padding for ambiguous states (e.g. 1 for probability  matrices,  0
           for derivative matrices) (input)
           count Number of transition matrices (input)

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleSetTransitionMatrix  (int  instance,  int  matrixIndex, const double * inMatrix,
       double paddedValue)
       Set  a  finite-time  transition  probability  matrix.  This  function  copies  a  finite-time  transition
       probability  matrix into a matrix buffer. This function is used when the application wishes to explicitly
       set  the  transition  probability  matrix  rather  than   using   the   beagleSetEigenDecomposition   and
       beagleUpdateTransitionMatrices  functions. The inMatrix array should be of size stateCount * stateCount *
       categoryCount and will contain one matrix for each rate category.

       Parameters
           instance Instance number (input)
           matrixIndex Index of matrix buffer (input)
           inMatrix Pointer to source transition probability matrix (input)
           paddedValue Value to be used for padding for ambiguous states (e.g. 1 for probability matrices, 0 for
           derivative matrices) (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleUpdatePartials (const  int  instance,  const  BeagleOperation  *  operations,  int
       operationCount, int cumulativeScaleIndex)
       Calculate  or  queue for calculation partials using a list of operations. This function either calculates
       or queues for calculation a list partials. Implementations supporting ASYNCH may queue these calculations
       while other implementations perform these operations immediately and in order.

       Parameters
           instance Instance number (input)
           operations BeagleOperation list specifying operations (input)
           operationCount Number of operations (input)
           cumulativeScaleIndex Index number of scaleBuffer to store accumulated factors (input)

       Returns
           error code

   BEAGLE_DLLEXPORT int beagleUpdatePartialsByPartition (const int instance, const BeagleOperationByPartition  *
       operations, int operationCount)
       Calculate  or  queue  for calculation partials using a list of partition operations. This function either
       calculates or queues for calculation a list partitioned partials. Implementations supporting  ASYNCH  may
       queue these calculations while other implementations perform these operations immediately and in order.

       Parameters
           instance Instance number (input)
           operations BeagleOperation list specifying operations (input)
           operationCount Number of operations (input)

       Returns
           error code

   BEAGLE_DLLEXPORT   int   beagleUpdateTransitionMatrices   (int   instance,   int   eigenIndex,  const  int  *
       probabilityIndices, const int * firstDerivativeIndices, const int * secondDerivativeIndices, const double
       * edgeLengths, int count)
       Calculate a list of transition probability matrices.  This  function  calculates  a  list  of  transition
       probabilities matrices and their first and second derivatives (if requested).

       Parameters
           instance Instance number (input)
           eigenIndex Index of eigen-decomposition buffer (input)
           probabilityIndices List of indices of transition probability matrices to update (input)
           firstDerivativeIndices List of indices of first derivative matrices to update (input, NULL implies no
           calculation)
           secondDerivativeIndices  List of indices of second derivative matrices to update (input, NULL implies
           no calculation)
           edgeLengths List of edge lengths with which to perform calculations (input)
           count Length of lists

       Returns
           error code

   BEAGLE_DLLEXPORT  int   beagleUpdateTransitionMatricesWithMultipleModels   (int   instance,   const   int   *
       eigenIndices,   const   int   *   categoryRateIndices,  const  int  *  probabilityIndices,  const  int  *
       firstDerivativeIndices, const int * secondDerivativeIndices, const double * edgeLengths, int count)
       Calculate a list of transition probability matrices with multiple models. This function calculates a list
       of transition probabilities matrices and their first and second derivatives (if requested).

       Parameters
           instance Instance number (input)
           eigenIndices List of indices of eigen-decomposition buffers to use for updates (input)
           categoryRateIndices List of indices of category-rate buffers to use for updates (input)
           probabilityIndices List of indices of transition probability matrices to update (input)
           firstDerivativeIndices List of indices of first derivative matrices to update (input, NULL implies no
           calculation)
           secondDerivativeIndices List of indices of second derivative matrices to update (input, NULL  implies
           no calculation)
           edgeLengths List of edge lengths with which to perform calculations (input)
           count Length of lists

       Returns
           error code

   BEAGLE_DLLEXPORT  int  beagleWaitForPartials  (const  int  instance,  const  int  *  destinationPartials, int
       destinationPartialsCount)
       Block until all calculations that write to the  specified  partials  have  completed.  This  function  is
       optional and only has to be called by clients that 'recycle' partials.

       If  used,  this  function  must  be called after a beagleUpdatePartials call and must refer to indices of
       'destinationPartials' that were used in a previous beagleUpdatePartials  call.  The  library  will  block
       until those partials have been calculated.

       Parameters
           instance Instance number (input)
           destinationPartials  List  of  the  indices of destinationPartials that must be calculated before the
           function returns
           destinationPartialsCount Number of destinationPartials (input)

       Returns
           error code

Author

       Generated automatically by Doxygen for BEAGLE from the source code.

Version 3.1.2                               Mon Apr 22 2024 09:45:12                    libhmsbeagle/beagle.h(3)